AmnSINE2

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID DF0000068
TE superfamily Unknown_LINE-dependent
TE class SINE
Species Amniota
Length 358
Kimura value 34.72
Tau index 0.0000
Description Aminiota SINE2
Comment The copy number ranges from ~100 in the human genome to ~178 in the chicken genome. 45% of human copies are in highly conserved regions. Shows distant similarity to Leu tRNA. Tentatively classified as SINE element. Inverted from UCON3 original. Reference coords 1-78:tRNA-Leu- TTG, 137-264:Deu core, remainder must match an as yet unknown LINE.
Sequence
GCCGGAGGGGATGGCTTAGTGGTCTAAGCATCAGGTTTGAAATACCTAGACTCCCTGGAACCACAGGTTCAAATCCCAGCAGGGTCGACTCAGCCCTTCATCCTTCCGAGGTAGATAAATTGAGTNCCACGCAGTTTACTGTGTGNGGGTCTTTCGGATGAGACCTTAAAAACCAAAGCCCTGTCTGCTCTGCGTGGACATTAAAGATCCCGTGGCGCTTTTCGTAAGAGTAGGGGTTTGCCCCGGTGCCCTTGGCCGAATTTCTGGAACCCGGCTGAAANCCCGGGGAAACCGAGAGCCTGGCTTATCCCTATAGGGTATTAGNCACCCTATAAAAGTTAAATTTATTTATTTATTT



TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family TFBS Start End Strand Score Matched sequence
AmnSINE2 NFKB1 232 244 + 1.31 AGGGGTTTGCCCC
AmnSINE2 IRF8 287 299 + 0.96 GGAAACCGAGAGC
AmnSINE2 IRF4 287 300 + -0.02 GGAAACCGAGAGCC
AmnSINE2 TRP2 162 182 + -1.61 GACCTTAAAAACCAAAGCCCT
AmnSINE2 TRP1 163 183 + -2.83 ACCTTAAAAACCAAAGCCCTG


TFBS enrichment in GRCh38

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.




GTEx

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.




TCGA

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).