MLT2B3

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID	DF0001031
TE superfamily	ERV3
TE class	LTR
Species	Primates
Length	554
Kimura value	14.74
Tau index	0.9340
Description	MLT2B3 Long Terminal Repeat for ERVL endogenous retrovirus
Comment	MLT2B3 is an ERVL LTR. However, a related LTR was "absorbed" by a mobile Ricksha DNA transposon; explaining this cross-Type homology. MLT2B3 contains a 50bp insertion compared to the otherwise closely related MLT2B2 variant.
Sequence	TGTGATGGTTAATATTAGGTGTCAACTTGATTGGATTGAAGGATGCCNAGATAGCTGGTAAAGTATTGTTTCTGGGTGTGTCTGTGAGGGTGTTGCCAGAGGAGATTAACATTTGAGTCAGTGGACTGGGAGAGGAAGACCCACCCTCANCGATGTGGGTGGGCACCATCCAATCGGCTGCCGGCNCGGCTAGAACAAAAAGGCAGAGGAAGGGCGAATTTGCTCTCTCTCCTGGAGCTGGGACACCCTTCTCCTCCTGCCCTCGGACATCAGANCTCCAGGTTCTTCGGCCTTTGGACTCTNGGACTTACACCAGCGGTTTNCCGGGCTCTCGGGCCTTCGGCCACAGACTGAAGGCTGCACCGTCGGCTTCCCTGCTTTTGAGGCTTTNGGACTCGGACTGAGCCACGCTACCGGCTTCCCTGGCTCCCCAGCTTGCAGACGGCCTATCGTGGGACTTCNCGGCCTTCGTGATCGTGTGAGCCAATTCCCCTAATAAATCCCCTTTATCTATCCTATTAGTTCTGTCCCTCTGGAGAACCCTGACTAATACA

TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family	TFBS	Start	End	Strand	Score	Matched sequence
MLT2B3	BHLH122	23	29	+	13.03	CAACTTG
MLT2B3	BATF::JUN	114	120	-	13.02	TGACTCA
MLT2B3	Atf3	114	120	-	12.99	TGACTCA
MLT2B3	BNC2	114	120	+	12.98	TGAGTCA
MLT2B3	BATF	114	120	-	12.94	TGACTCA
MLT2B3	bowl	410	417	+	12.92	GCTACCGG
MLT2B3	NFYC	28	34	-	12.90	CCAATCA
MLT2B3	SATB1	493	499	+	12.89	CTAATAA
MLT2B3	Klf3/8/12	74	82	-	12.78	GACACACCC
MLT2B3	Gli1	156	165	-	12.67	TGCCCACCCA

1 2 3 4 5 6 7 ... 18

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).