MLT2B3

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID	DF0001031
TE superfamily	ERV3
TE order	LTR
Species	Primates
Length	554
Kimura value	14.74
Tau index	0.9340
Description	MLT2B3 Long Terminal Repeat for ERVL endogenous retrovirus
Comment	MLT2B3 is an ERVL LTR. However, a related LTR was "absorbed" by a mobile Ricksha DNA transposon; explaining this cross-Type homology. MLT2B3 contains a 50bp insertion compared to the otherwise closely related MLT2B2 variant.
Sequence	TGTGATGGTTAATATTAGGTGTCAACTTGATTGGATTGAAGGATGCCNAGATAGCTGGTAAAGTATTGTTTCTGGGTGTGTCTGTGAGGGTGTTGCCAGAGGAGATTAACATTTGAGTCAGTGGACTGGGAGAGGAAGACCCACCCTCANCGATGTGGGTGGGCACCATCCAATCGGCTGCCGGCNCGGCTAGAACAAAAAGGCAGAGGAAGGGCGAATTTGCTCTCTCTCCTGGAGCTGGGACACCCTTCTCCTCCTGCCCTCGGACATCAGANCTCCAGGTTCTTCGGCCTTTGGACTCTNGGACTTACACCAGCGGTTTNCCGGGCTCTCGGGCCTTCGGCCACAGACTGAAGGCTGCACCGTCGGCTTCCCTGCTTTTGAGGCTTTNGGACTCGGACTGAGCCACGCTACCGGCTTCCCTGGCTCCCCAGCTTGCAGACGGCCTATCGTGGGACTTCNCGGCCTTCGTGATCGTGTGAGCCAATTCCCCTAATAAATCCCCTTTATCTATCCTATTAGTTCTGTCCCTCTGGAGAACCCTGACTAATACA

TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family	TFBS	Start	End	Strand	Score	Matched sequence
MLT2B3	KLF9	72	82	-	14.09	GACACACCCAG
MLT2B3	TBX3	17	25	+	13.87	AGGTGTCAA
MLT2B3	klu	152	162	-	13.79	CCACCCACATC
MLT2B3	fos-1	114	120	-	13.76	TGACTCA
MLT2B3	ERF6	179	185	+	13.72	TGCCGGC
MLT2B3	DUX4	28	38	-	13.70	CAATCCAATCA
MLT2B3	PK24580.1	179	185	-	13.69	GCCGGCA
MLT2B3	odd-2	410	417	+	13.67	GCTACCGG
MLT2B3	Klf6-7-like	67	86	-	13.58	CACAGACACACCCAGAAACA
MLT2B3	MYB99	14	21	-	13.30	CACCTAAT

1 2 3 4 5 ... 18

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).