MLT1L

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID	DF0001023
TE superfamily	MaLR
TE class	LTR
Species	Theria_mammals
Length	610
Kimura value	31.89
Tau index	0.9557
Description	MLT1L Long Terminal Repeat for ERVL-MaLR retrotransposon
Comment	MLT1L has 5 bp TSDs. Note that a full-length ERV-MaLR (Mammalian apparent LTR retrotransposon) element is derived from an ERV (Endogenous Retrovirus), but only contains the Gag gene (that is, no Pol or Env).
Sequence	TGTGGCAGACACTGTTGGTTGCCTACCCAACAGCCATTCTCCCCTTCTTCCTTGCTAACAGAACCCCGATTTTGTTCAGGTATCNGGCGGCCATGTGCTTCAGGGGAGGCTGGNCCCCTCCCCAGCCCCAGGGGGTGAATCNTGATTGGTCTAAGCCAATCATGGTAATCCCATTCCCCTTGCCAGTGATTGGTTTAGGAATGGGCATGTGACNCAATTCTGGCCAATGAGACGTGAGGGGAAGTCTGCTGGGGGGCTTCTGGGAAAGNTTTCCTCGCTCTTAAAAAAAGGACATAAGGAAGAGATGTCCTCTTTTCTTGCCTCTGGACGTTGTCGTGTGNGGATGTGATGCCTGGAGCTGCNGCAGCCATCTTGCGACCATGAGGGGACAAGCCTGAGAGGAAAAGCCAACACGCTGAGGATGGCAGAGCGGAAAGATGGAAAGAACCTGGGTCCTTGATGACATCGTTGAGCCGCTGAATTAACCAACCCTGGAACCGCCCTACCTCCGGACTTCTTGTTATGTGAGATAATAAATTTTCCTTATTGTTTAAGCCANTTTGAGTTGGGTTTTCTGTTACTTGCAGCCGAAAGCATCCTAACTGATACA

TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family	TFBS	Start	End	Strand	Score	Matched sequence
MLT1L	DOF5.8	285	303	-	14.03	TCTTCCTTATGTCCTTTTT
MLT1L	TFAP2C	124	136	-	14.02	ACCCCCTGGGGCT
MLT1L	HAP3	187	195	+	14.00	TGATTGGTT
MLT1L	TFAP2A	125	135	-	13.91	CCCCCTGGGGC
MLT1L	DUX4	152	162	+	13.89	TAAGCCAATCA
MLT1L	KLF14	115	123	-	13.88	GGGGAGGGG
MLT1L	ZmbZIP72	458	467	-	13.86	GATGTCATCA
MLT1L	ZNF257	315	324	-	13.80	GAGGCAAGAA
MLT1L	Stat5a	258	266	-	13.75	TTCCCAGAA
MLT1L	TFAP2A	124	136	-	13.69	ACCCCCTGGGGCT

1 2 3 4 5 6 7 ... 26

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).