MLT1L

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID	DF0001023
TE superfamily	MaLR
TE class	LTR
Species	Theria_mammals
Length	610
Kimura value	31.89
Tau index	0.9557
Description	MLT1L Long Terminal Repeat for ERVL-MaLR retrotransposon
Comment	MLT1L has 5 bp TSDs. Note that a full-length ERV-MaLR (Mammalian apparent LTR retrotransposon) element is derived from an ERV (Endogenous Retrovirus), but only contains the Gag gene (that is, no Pol or Env).
Sequence	TGTGGCAGACACTGTTGGTTGCCTACCCAACAGCCATTCTCCCCTTCTTCCTTGCTAACAGAACCCCGATTTTGTTCAGGTATCNGGCGGCCATGTGCTTCAGGGGAGGCTGGNCCCCTCCCCAGCCCCAGGGGGTGAATCNTGATTGGTCTAAGCCAATCATGGTAATCCCATTCCCCTTGCCAGTGATTGGTTTAGGAATGGGCATGTGACNCAATTCTGGCCAATGAGACGTGAGGGGAAGTCTGCTGGGGGGCTTCTGGGAAAGNTTTCCTCGCTCTTAAAAAAAGGACATAAGGAAGAGATGTCCTCTTTTCTTGCCTCTGGACGTTGTCGTGTGNGGATGTGATGCCTGGAGCTGCNGCAGCCATCTTGCGACCATGAGGGGACAAGCCTGAGAGGAAAAGCCAACACGCTGAGGATGGCAGAGCGGAAAGATGGAAAGAACCTGGGTCCTTGATGACATCGTTGAGCCGCTGAATTAACCAACCCTGGAACCGCCCTACCTCCGGACTTCTTGTTATGTGAGATAATAAATTTTCCTTATTGTTTAAGCCANTTTGAGTTGGGTTTTCTGTTACTTGCAGCCGAAAGCATCCTAACTGATACA

TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family	TFBS	Start	End	Strand	Score	Matched sequence
MLT1L	ZNF582	574	592	+	30.81	TCTGTTACTTGCAGCCGAA
MLT1L	Stat5b	258	266	-	16.36	TTCCCAGAA
MLT1L	MAZ	115	122	+	16.08	CCCCTCCC
MLT1L	SP1	115	123	-	16.06	GGGGAGGGG
MLT1L	SP4	115	123	-	15.85	GGGGAGGGG
MLT1L	NFYB	222	230	-	15.74	TCATTGGCC
MLT1L	ZNF148	115	124	+	15.61	CCCCTCCCCA
MLT1L	sug	246	257	-	15.25	GCCCCCCAGCAG
MLT1L	STAT3	258	266	+	15.20	TTCTGGGAA
MLT1L	STAT1	258	266	+	15.13	TTCTGGGAA

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Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).