MIR3

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID DF0000974
TE superfamily L2-end
TE class SINE
Species Mammalia
Length 208
Kimura value 34.83
Tau index 0.7446
Description MIR3 (Mammalian-wide Interspersed Repeat 3)
Comment MIR3 is a pan-mammalian SINE with a 5' end derived from a tRNA, a central deeply-conserved CORE region (shared with other MIRs), and a 3' terminal ~55bp related to an L3 LINE.
Sequence
CTGGCAGAGTGGCTGAGCAGAGAGAGCACGGACTGGGAGTCAGGAGACCTGGGTTCTAGTCCCGGCTCTGCCACTAACTNGCTGTGTGACCTTGGGCAAGTCACTTCACCTCTCTGGGCCTCAGTTTCCTCATCTGTAAAATGAGGGGGTTGGACTAGATGATCTCTAAGGTCCCTTCCAGCTCTGACATTCTATGATTCTATGATTC



TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family TFBS Start End Strand Score Matched sequence
MIR3 PI 124 137 - 11.67 ACAGATGAGGAAAC
MIR3 ASR1 113 121 - 11.43 AGGCCCAGA
MIR3 VIP1 176 185 + 11.38 TTCCAGCTCT
MIR3 M1BP 82 92 - 11.37 AGGTCACACAG
MIR3 AP1 125 137 - 11.35 ACAGATGAGGAAA
MIR3 Trl 20 28 + 11.20 GAGAGAGCA
MIR3 ZAT10 66 75 + 11.18 CTCTGCCACT
MIR3 SPIB 101 113 + 10.96 TCACTTCACCTCT
MIR3 ftz-f1 88 95 + 10.94 GACCTTGG
MIR3 PAX5 84 91 + 10.91 GTGTGACC


TFBS enrichment in GRCh38

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.




GTEx

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.




TCGA

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).