MIR3

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID DF0000974
TE superfamily L2-end
TE class SINE
Species Mammalia
Length 208
Kimura value 34.83
Tau index 0.7446
Description MIR3 (Mammalian-wide Interspersed Repeat 3)
Comment MIR3 is a pan-mammalian SINE with a 5' end derived from a tRNA, a central deeply-conserved CORE region (shared with other MIRs), and a 3' terminal ~55bp related to an L3 LINE.
Sequence
CTGGCAGAGTGGCTGAGCAGAGAGAGCACGGACTGGGAGTCAGGAGACCTGGGTTCTAGTCCCGGCTCTGCCACTAACTNGCTGTGTGACCTTGGGCAAGTCACTTCACCTCTCTGGGCCTCAGTTTCCTCATCTGTAAAATGAGGGGGTTGGACTAGATGATCTCTAAGGTCCCTTCCAGCTCTGACATTCTATGATTCTATGATTC



TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family TFBS Start End Strand Score Matched sequence
MIR3 ESRRA 87 95 - 15.37 CCAAGGTCA
MIR3 pita 52 69 - 15.12 AGAGCCGGGACTAGAACC
MIR3 Esrrg 87 95 - 14.81 CCAAGGTCA
MIR3 ERR 87 94 - 14.77 CAAGGTCA
MIR3 ZNF768 108 116 + 14.62 ACCTCTCTG
MIR3 ESRRB 86 95 - 14.41 CCAAGGTCAC
MIR3 Hr39 87 94 - 14.02 CAAGGTCA
MIR3 hr3 84 91 - 13.92 GGTCACAC
MIR3 NR5A1 87 98 - 13.84 TGCCCAAGGTCA
MIR3 sex-1 86 93 - 13.51 AAGGTCAC


TFBS enrichment in GRCh38

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.




GTEx

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.




TCGA

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).