MIR3

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID DF0000974
TE superfamily L2-end
TE class SINE
Species Mammalia
Length 208
Kimura value 34.83
Tau index 0.7446
Description MIR3 (Mammalian-wide Interspersed Repeat 3)
Comment MIR3 is a pan-mammalian SINE with a 5' end derived from a tRNA, a central deeply-conserved CORE region (shared with other MIRs), and a 3' terminal ~55bp related to an L3 LINE.
Sequence
CTGGCAGAGTGGCTGAGCAGAGAGAGCACGGACTGGGAGTCAGGAGACCTGGGTTCTAGTCCCGGCTCTGCCACTAACTNGCTGTGTGACCTTGGGCAAGTCACTTCACCTCTCTGGGCCTCAGTTTCCTCATCTGTAAAATGAGGGGGTTGGACTAGATGATCTCTAAGGTCCCTTCCAGCTCTGACATTCTATGATTCTATGATTC



TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family TFBS Start End Strand Score Matched sequence
MIR3 svp 87 93 - 12.82 AAGGTCA
MIR3 ZNF574 106 119 - 12.75 GCCCAGAGAGGTGA
MIR3 ZNF416 111 120 + 12.40 TCTCTGGGCC
MIR3 NRG1 170 177 - 12.30 AAGGGACC
MIR3 ARG81 36 42 - 12.30 TGACTCC
MIR3 AGL15 125 140 + 12.20 TTTCCTCATCTGTAAA
MIR3 ss 83 90 + 12.10 TGTGTGAC
MIR3 ZNF692 114 121 - 12.00 AGGCCCAG
MIR3 AG 125 140 + 11.79 TTTCCTCATCTGTAAA
MIR3 nhr-142 84 91 - 11.70 GGTCACAC


TFBS enrichment in GRCh38

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.




GTEx

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.




TCGA

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).