MER4B

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID	DF0000797
TE superfamily	ERV1
TE class	LTR
Species	Haplorrhini
Length	610
Kimura value	12.22
Tau index	0.9326
Description	MER4B Long Terminal Repeat for ERV1 endogenous retrovirus
Comment	Note that MER stands for MEdium Reiteration frequency interspersed repeat. As such, MERs as a group are a grab bag of DNA transposons and retrotransposons.
Sequence	TGTAAACCAAAAATAAAATTCTAAGCCCCCCAACCATCTGAATGGACCCCTCCTCTCGGCCAAGGGCATTCCAAAGTTAACCTGAAAAACTGGTTCAGGCCATGATGGGAAGNGGGGGTCGGACATGCCTCATTATACCCTCCTCCCTTTTGGAATTCAGGNANAGCCGACCAGCATTAACATCAACACAGACCTTAAGTCTGATAAGAAACATTTACAATCTATTCTCTCTGAAGCCTGCTACCTGGAGGCTTCATCTGCATGATAAAACCTTGGTCTCCACAACCCCTTATCGTAACCCAGACATTCCTTTCTATTGATAATAACTCTTTCAACCAATTGCCAATCAGAAAATCTTTAAATCTACCTATGACCTGGAAGCCCCCGCTTCGAGTTGTCCCGCCTTTCCGGACCGAACCAATGTACATCTTACATGTATTGATTGATGTCTCATGTCTCCCTAAAATGTATAAAACCAAGCTGTACCCCGACCACCTTGGGCACATGTTCTCAGGACCTCCTGAGGCTGTGTCACGGGCGCGTCCTTAACCTTGGCAAAATAAACTTTCTAAATTGATTGAGACCTGTCTCAGATACTTTTGGGTTCACA

TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family	TFBS	Start	End	Strand	Score	Matched sequence
MER4B	GCR1	376	383	+	14.47	TGGAAGCC
MER4B	ERF018	166	173	+	14.29	GCCGACCA
MER4B	ZBTB7C	489	496	+	14.24	CGACCACC
MER4B	elt-2	202	209	-	14.16	TCTTATCA
MER4B	MAZ	47	54	+	14.06	CCCCTCCT
MER4B	dmd-10	208	215	-	14.04	AATGTTTC
MER4B	ZNF263	141	147	-	13.83	GGGAGGA
MER4B	POU2F1::SOX2	255	271	+	13.75	CATCTGCATGATAAAAC
MER4B	ONECUT1	437	445	-	13.46	CAATCAATA
MER4B	ZNF770	522	529	-	13.45	CAGCCTCA

1 2 3 4 5 ... 22

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).