MER110A

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID DF0000706
TE superfamily ERV1
TE class LTR
Species Eutheria
Length 468
Kimura value 25.84
Tau index 0.0000
Description MER110A Long Terminal Repeat for ERV1 endogenous retrovirus
Comment Similar to MER110 in the 3' region, and more modestly, to MER90a across that same region. Note that MER stands for MEdium Reiteration frequency interspersed repeat. As such, MERs as a group are a grab bag of DNA transposons and retrotransposons.
Sequence
TGAGAACCGAAACCATCTACCACCCACACAGCTTACTGNCTGTCTACATTAACATGACTTTACTATTCCACTGTCTTCATCAACATGACTTTACTATTCCAGGAAACTCTTGCCCAGGAAGATAAAAGTTGCAAATAACTTTATTGTTCATTNCAGGAACTTCCCGAAAGACCCATCAACTCTTCAATAGAAAGCATCAAACGACAGTTTATCCCCAAGACTCTTTGAANCCCTCGCCTCAAAATCCTCGCCTTGCTGTGTCTNCGTCCACCAATCCTAAACTATTATATCATGATCCTTACCCAATCCTAATCAAGCCCCCGCATTGAAAGACCCGCCTTAAACCAGACTCCAAAATCTCAATAAATATCCCGACTTTGCCCTCCCTCCTCTGAGACGCTACTAAGACTCTGTAAGGTGGTGCTCTCCCTTACCGCGGTAAGCAATAAACTCAGCTTTGTCTTATCA



TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family TFBS Start End Strand Score Matched sequence
MER110A klu 20 30 + 18.79 CCACCCACACA
MER110A ZNF257 231 240 - 16.80 GAGGCGAGGG
MER110A ATMYB31 14 28 + 16.36 CATCTACCACCCACA
MER110A MYB31 14 28 + 16.36 CATCTACCACCCACA
MER110A Stat4 97 106 + 15.84 TTCCAGGAAA
MER110A STAT1 97 105 + 15.62 TTCCAGGAA
MER110A STAT1::STAT2 2 14 - 14.73 GGTTTCGGTTCTC
MER110A elt-3 461 468 + 14.52 TCTTATCA
MER110A Stat5a 97 105 + 14.42 TTCCAGGAA
MER110A IRF6 6 14 + 14.24 ACCGAAACC


TFBS enrichment in GRCh38

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.




GTEx

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.




TCGA

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).