SVA_B
Basic information Differential Expression Stage analysis Survival analysis Correlation analysis| DF ID | DF0001068 |
|---|---|
| TE superfamily | SVA |
| TE class | Retroposon |
| Species | Hominidae |
| Length | 1383 |
| Kimura value | 5.80 |
| Tau index | 0.6953 |
| Description | Composite retroelement: (SINE-R + VNTR + Alu), SVA_B subfamily |
| Comment | SVA retroelements are hominid-specific chimeras, some of which are still active in the human population. These SINEs are a unique combination of features. The 5' end begins with hexamer repeats, followed by two Alus in reverse orientation. The center is comprised of a number of VNTR regions (Variable Number of Tandem Repeats) that may span a few hundred basepairs, up to 2000bp. The 3' end is formed by a portion of a HERVK LTR (the SINE-R feature). |
| Sequence |
CTCTCCCTCTCCCTCTCCCTCTCCCTCTCCCTCTCCCTCTCCCTNTCCCCTCTTTCCACGGTCTCCCTCTGATGCCGAGCCGAGGCTGGACTGTACTGCCGCCATCTCGGCTCACTGCAACCTCCCTGCCTGATTCTCCTGCCTCAGCCTGCCGAGTGCCTGGGATTGCAGGCGCGCGCCGCCACGCCTGACTGGTTTTCGTATTTTTTGGTGGAGACGGGGTTTCGCCGTGTTGGCCGGGCTGGTCTCCAGCTCCTGACCGCGAGTGATCTGCCNGCCTCGGCCTCCCGAGGTGCCGGGATTGCAGACGGAGTCTCGCTCACTCAGTGCTCAATGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCGCTACAACCTCCACCTCCCAGCCGCCTGCCTTGGCCTCCCAAAGTGCCGAGATTGCAGCCTCTGCCCGGCCGCCACCCCGTCTGGGAAGTGAGGAGCGTCTCTGCCTGGCCGCCCATCGTCTGGGATGTGAGGAGCCCCTCTGCCCGGCCGCCCAGTCTGGGAAGTGAGGAGCGCCTCTTCCCGGCCGCCATCCCGTCTGGGAAGTGAGGAGCGTCTCTGCCCGGCCGCCCATCGTCTGGGATGTGGGGAGCGCCTCTGCCCCGCCGCCCCGTCTGGGANGTGAGGAGCGCCTCTGCCCGGCCAGCCGCCCCGTCTGGGAGGTGAGGAGGTCAGCCCCCCGCCCGGCCAGCCGCCCCGTCCGGGAGGAGGTGGGGGGNNCAGCCCCCCGCCCGGCCAGCCGCCCCGTCCGGGAGGTGGGGGGCGCCTCTGCCCGGCCGCCCCGTCTGGGAAGTGAGGAGCCCCTCTGCCCGGCCGCCACCCCGTCTGGGAGGTGTACCCAACAGCTCATTGAGAACGGGCCATGATGACGATGGCGGTTTTGTCGAATAGAAAAGGGGGAAATGTGGGGAAAAGAAAGAGAGATCAGATTGTTACTGTGTCTGTGTAGAAAGAAGTAGACATAGGAGACTCCATTTTGTTCTGTACTAAGAAAAATTCTTCTGCCTTGGGATGCTGTTAATCTATAACCTTACCCCCAACCCCGTGCTCTCTGAAACATGTGCTGTGTCCACTCAGGGTTAAATGGATTAAGGGCGGTGCAAGATGTGCTTTGTTAAACAGATGCTTGAAGGCAGCATGCTCGTTAAGAGTCATCACCACTCCCTAATCTCAAGTACCCAGGGACACAAACACTGCGGAAGGCCGCAGGGTCCTCTGCCTAGGAAAACCAGAGACCCTTGTTCACATGTTTATCTGCTGACCTTCCCTCCACTATTGTCCTATGACCCTGCCAAATCCCCCTCTCCGAGAAACACCCAAGAATGATCAATAAATACTAAAAAAAAAAAAA
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TF motifs of the concenus sequence
Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.
| TE_family | TFBS | Start | End | Strand | Score | Matched sequence |
|---|---|---|---|---|---|---|
| SVA_B | TRP2 | 1358 | 1378 | + | -0.91 | ATCAATAAATACTAAAAAAAA |
| SVA_B | BPC6 | 937 | 957 | - | -2.86 | ATCTCTCTTTCTTTTCCCCAC |
| SVA_B | RARA | 692 | 709 | + | -3.08 | GAGGTGAGGAGGTCAGCC |
| SVA_B | TRP1 | 1359 | 1379 | + | -5.01 | TCAATAAATACTAAAAAAAAA |
| SVA_B | NR1H2::RXRA | 1049 | 1065 | - | -6.39 | TAAGGTTATAGATTAAC |
| SVA_B | BPC5 | 930 | 959 | + | -43.99 | GGGAAATGTGGGGAAAAGAAAGAGAGATCA |
TFBS enrichment in GRCh38
Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.
