AluYc3

Basic information Differential Expression Stage analysis Survival analysis Correlation analysis

DF ID DF0000058
TE superfamily Alu
TE class SINE
Species Hominoidea
Length 300
Kimura value 3.98
Tau index 0.9864
Description AluYc3 subfamily
Comment Alu elements derive from a pair of internally-deleted 7SL RNA monomers that are joined by an A-rich linker. AluYc2, AluYc3, and AluYd3a1 are identical. Naming convention suggests AluYc2 is preferred, as seq differs from AluY at 2 positions.
Sequence
GGCCGGGCGCGGTGGCTCACGCTTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGAGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA



TF motifs of the concenus sequence

Use FIMO to detect transcription factor motifs in the concenus sequence of the TE family.

TE_family TFBS Start End Strand Score Matched sequence
AluYc3 luna 127 135 - 15.26 ACCACGCCC
AluYc3 Klf3/8/12 127 135 - 15.24 ACCACGCCC
AluYc3 ZNF135 69 82 - 14.93 TCTCGATCTCCTGA
AluYc3 KLF3 127 136 - 14.83 CACCACGCCC
AluYc3 Spps 197 207 - 14.75 GCTCCGCCTCC
AluYc3 ZNF257 172 181 + 14.53 GAGGCAGGAG
AluYc3 KLF3 5 14 - 14.43 CACCGCGCCC
AluYc3 CRF4 131 140 - 14.36 CCGCCACCAC
AluYc3 KLF2 127 134 - 14.29 CCACGCCC
AluYc3 EREB71 5 14 - 14.22 CACCGCGCCC


TFBS enrichment in GRCh38

Use Fisher's exact test to perform enrichment analysis of transcription factor binding sites in the TE family of GRCh38.




GTEx

The promoter activity across 46 body sites from The Genotype-Tissue Expression (GTEx) project.




TCGA

The promoter activity across 33 cancer types from The Cancer Genome Atlas (TCGA).